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anti-igg2-af488  (SouthernBiotech)


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    SouthernBiotech anti-igg2-af488
    Anti Igg2 Af488, supplied by SouthernBiotech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti-igg2-af488/product/SouthernBiotech
    Average 90 stars, based on 1 article reviews
    anti-igg2-af488 - by Bioz Stars, 2026-03
    90/100 stars

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    igg2 af488  (SouthernBiotech)
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    SouthernBiotech igg2 af488
    In ECs, HIV-specific memory B cell responses are mainly of the IgG1 isotype. Percentage of antibody secreting B cells specific for HIV-Env antigens (gp140Yu2b, gp41S30 or gp160THO) and Influenza vaccine antigen (Flu, 2015 VAXIGRIP vaccine) presented according to the Ab isotype: (a) total IgG +, (b) IgG1 +, (c) <t>IgG2</t> + and (d) IgG3 + antigen-specific ASC. Each individual is represented by a specific dot on each graph (shape and color). Statistical significance was calculated using a Kruskal-Wallis test followed by a Dunn's test (*p < 0.05). Bars indicate median values.
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    In ECs, HIV-specific memory B cell responses are mainly of the IgG1 isotype. Percentage of antibody secreting B cells specific for HIV-Env antigens (gp140Yu2b, gp41S30 or gp160THO) and Influenza vaccine antigen (Flu, 2015 VAXIGRIP vaccine) presented according to the Ab isotype: (a) total IgG +, (b) IgG1 +, (c) IgG2 + and (d) IgG3 + antigen-specific ASC. Each individual is represented by a specific dot on each graph (shape and color). Statistical significance was calculated using a Kruskal-Wallis test followed by a Dunn's test (*p < 0.05). Bars indicate median values.

    Journal: EBioMedicine

    Article Title: HIV-Specific B Cell Frequency Correlates with Neutralization Breadth in Patients Naturally Controlling HIV-Infection

    doi: 10.1016/j.ebiom.2017.05.029

    Figure Lengend Snippet: In ECs, HIV-specific memory B cell responses are mainly of the IgG1 isotype. Percentage of antibody secreting B cells specific for HIV-Env antigens (gp140Yu2b, gp41S30 or gp160THO) and Influenza vaccine antigen (Flu, 2015 VAXIGRIP vaccine) presented according to the Ab isotype: (a) total IgG +, (b) IgG1 +, (c) IgG2 + and (d) IgG3 + antigen-specific ASC. Each individual is represented by a specific dot on each graph (shape and color). Statistical significance was calculated using a Kruskal-Wallis test followed by a Dunn's test (*p < 0.05). Bars indicate median values.

    Article Snippet: Cell viability was evaluated using LIVE/DEAD® (ThermoFisher Scientific) and the following Abs were used: CD19-APCCy7 (SJ25C1), CD21-APC (B-ly4), CD27-PE (M-T271), IgD-PECF594 (IA6-2), IgG-BV605 (G18-145), CD38-V450 (HB7) (all from BD biosciences), IgM-AF700 (CH2, Exbio) and IgG2-AF488 (HP6002, Southern Biotech).

    Techniques:

    In HLA-B*57 + ECs, the frequency of HIV-specific B cells correlates with the neutralization of tier-2 T/F virus. (a) Association of HIV gp140-specific B cell frequency (among IgG + B cells) and percent of neutralization for all HIV strains tested (top panel) or T/F HIV strains (bottom panel) for all ECs (Total EC), HLA-B*57 + and HLA-B*57 − ECs. (*) p < 0.05. (b) Spearman correlation matrices between the frequency of gp140- and gp41-specific B cell of various IgG isotypes and the percentage of neutralized strains (All strains) or T/F strains and the frequency of Env-specific B cell of various IgG subtypes. Left panel HLA-B*57 + and right panel HLA-B*57 − ECs. Strength and significance are represented as size and color intensity: blue for positive correlation and red for negative correlation. The numbers are p values.

    Journal: EBioMedicine

    Article Title: HIV-Specific B Cell Frequency Correlates with Neutralization Breadth in Patients Naturally Controlling HIV-Infection

    doi: 10.1016/j.ebiom.2017.05.029

    Figure Lengend Snippet: In HLA-B*57 + ECs, the frequency of HIV-specific B cells correlates with the neutralization of tier-2 T/F virus. (a) Association of HIV gp140-specific B cell frequency (among IgG + B cells) and percent of neutralization for all HIV strains tested (top panel) or T/F HIV strains (bottom panel) for all ECs (Total EC), HLA-B*57 + and HLA-B*57 − ECs. (*) p < 0.05. (b) Spearman correlation matrices between the frequency of gp140- and gp41-specific B cell of various IgG isotypes and the percentage of neutralized strains (All strains) or T/F strains and the frequency of Env-specific B cell of various IgG subtypes. Left panel HLA-B*57 + and right panel HLA-B*57 − ECs. Strength and significance are represented as size and color intensity: blue for positive correlation and red for negative correlation. The numbers are p values.

    Article Snippet: Cell viability was evaluated using LIVE/DEAD® (ThermoFisher Scientific) and the following Abs were used: CD19-APCCy7 (SJ25C1), CD21-APC (B-ly4), CD27-PE (M-T271), IgD-PECF594 (IA6-2), IgG-BV605 (G18-145), CD38-V450 (HB7) (all from BD biosciences), IgM-AF700 (CH2, Exbio) and IgG2-AF488 (HP6002, Southern Biotech).

    Techniques: Neutralization, Virus